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ARTESUNATE

    
　

Structure: C19H28O8

Molecular Weight: 384.4

Chemical name:
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]1,2-benzodioxepin-10-ol,hydrogen succinate; CAS Reg. N° 88495-63-O.

Chemical characteristics:



Lipophylic substance : Very slightly soluble in water; very soluble in dichloromethane R; freely soluble in ethanol (~750 g/l) and acetone.

Melting point : 144 °C

Pharmacalogical properties:

Remark: Artesunate is synthetised by reacting DHA and succinic acid anhydride in alkaline medium. This type of reation invariably yields an ester linkage in alpha configuration.

　

 　 　
　 　 　 　
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