1/2 /3-4/ 5-9/Aa-Am/An-Az/B/Ca-Ce/Cf-Cz/Da-Dh/Di-Dz/E/F/G/H/I/J/K/L/M/N/O/Pa-Pf/ /Pj-Po/Pp-Pz/Q/R/Sa-Ss/St-y/Ta-Th/Ti-Tz/U/V/W/X/Y/Z / Chinese spelling
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Micro Fish Collagen Peptide -New Tools for Remediation and Prevention skin |
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Certicficate of Analysis Item: MicroFishcollagen peptide
Quality Control Dept: Inspector: W.D. Shi Analyst: G.X. Chen
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| Microcollagen Pentapeptides: Fibroblast collagen production has been reported to be stimulated by a pentapeptide fragment of the collagen molecule. 39 Application of this pentapeptide (characeterized by Katayama and colleagues as lys-Thr-Thr-Lys-Ser) demonstrated an increase in production of soluble collagen IV by as much as 427% by fibroblasts in a biopsy sample from a 63 year old female donor. Glycosaminoglycan production in the same sample was increased by 367% above control. Ex vivo testing of the pentapeptide (3% concentration) on a panel of 35 subjects for a period of six months demonstrated significant to highly significant changes (percent wrinkle with an area >200µm, wrinkle density, roughness, volume of main wrinkle, mean depth of main wrinkle) over a placebo cream as well as a commercial 5% vitamin C product. |
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Peptides (small protein polymers) have been shown to counteract the degradation of dermal collagen, resulting in a significant change in the appearance of moderate to deep lines and wrinkles. As collagen fibrils are broken down through natural biological process, peptide portions or by-products of this catabolic process act as signals or messenger molecules in the formation of new collagen fibrils by the fibroblasts. Identification and incorporation of very specific peptide sequences has demonstrated biological activity in relationship to collagen formation in both in vitro and ex vivo human tests. The molecule shown to have this signaling power is a pro-collagen I terminal sequence consisting of the amino acids; Lysine - Threonine - Threonine - Lysine - Serine Lys-thr-thr-lys-ser The small molecular size of the peptide linked to a palmitic acid chain allows for increased penetration into the top stratum corneum layers of the skin. |
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| Packing &loading | ||||||||||||||||||||||||||||||||||
| 25kg net/ Drum | ||||||||||||||||||||||||||||||||||
| This data is only for your information purposes and does not imply guarantee for a certain application. | ||||||||||||||||||||||||||||||||||
| If you need an indicative price to your country, please kindly advise the annual quantity needed, destination port and we will send you our soonest CNF(Cost + Freight) price. Your indication for a workable price level will sure speed up our fastest service for you | ||||||||||||||||||||||||||||||||||
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We really need to get
feed back from our customers in order to improve our performances. Best regards from SHENZHEN , China Mr. JEFFERY TSUI |
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| Material Safety Data Sheet | ||||||||||||||||||||||||||||||||||
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