ARTEMISININ

Molecular weight: 282.3

Chemical name:
3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3, 12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin-10(3H)-one; CAS Reg. N?63968-64-9

Lipophylic substance : Soluble in ethanol and hexane.

Description : white crystalline powder

Melting range : 150 C?- 153 C?o:p>

Pharmacological properties: Artemisinin acts as a blood schizontocide and therefore kills malaria parasites.

Artemisinin is the product extracted from the dry leaves of Artemsisia Annua (sweet wormwood). This plant has to be grown each year stating from seeds. The plant is peculiar in its behaviour. Nicely grown-up plants may be devoid of Artemisinin. In order that this product is synthetised by the plant special agricultural and climatological conditions must be respected. The plant can grow in many places but it may not contain Artemisinin.
For example: Visitors of the ancient palaces in the Forbidden City in Beijing can find nice artemisia annua plants pushing left and right as weeds, but these plants do not contain artemisinin.
Best results have been obtained in plantations (North Vietnam, mainly in the vicinity of Hanoi) or in wild plants (the plants collected from the steep hills around You Yang in the Chongqing province in China where the best plant grows at altitudes above 1000 m).?The highest yields per ton dry leaves comes from cultures in Tanzania.

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