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DIHYDROARTEMISININ (DHA)

   
  Structure: C15H24O5

Molecular weight: 284.4

Chemical name:
(3R,5aS,6R,8aS,9R,10S,12R,12aR)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]- 1,2-benzodioxepin-10-ol; CAS Reg. No. 81496-81-3.

Chemical characteristics: The product exists as a mixture of a and b epimers.



Lipophilyc substance : Practically insoluble in water; slightly soluble in acetonitrile, soluble in ethanol and dichloromethane.

Description: Colourless needles or a white, crystalline powder.

Melting point: about 140 .

Category: Antimatarial.

Storage: Dihydroartemisinin should be kept in a well-closed container, protected from light and stored in a cool place.

Requirements: Dihydroartemisinin contains not less than 98.0% and not more than the equivalent of 102.0% of C15H

 

   
       
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  Material Safety Data Sheet    
       
  Related Information and Materials    
  A comparison of three different dihydroartemisinin formulations for the treatment of acute uncomplicated falciparum malaria in Thailand    
  Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria    
  A Clinical Trial of Dihydroartemisinin for the Treatment of Acute Uncomplicated Falciparum Malaria in Thailand : A Comparison of 3 Different Formulations    
       
     
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