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   FOSINOPRIL SODIUM    
 

  CERTIFICATE OF ANALYSIS

PRODUCTFosinopril Sodium

 

BATCH NO       

 

 20040615

 

DATE OF PRODUCTION

 

  Jun.15, 2004

 

 

PACKING

 

 1KG/TIN

 

DATE OF VALIDITY

 

  Sun.15, 2007

 

QUANTITY        

 

 2KGS

 

DATE OF REPORT

 

  Jun.18, 2004

 

    TESTS    

 

     STANDARD  

 

 

 RESULTS    

 

1.CHARACTERISTICS

 

WHITE CRYSTALLINE POWDER

 

 COMPLIES

 

2. IDENTIFICATION

 

MEETS THE REQUIREMENTS

 

 COMPLIES

 

3. MELTING RANGE

 

190°C ~ 197°C

 

 192°C ~ 194°C

 

4. LOSS ON DRYING

 

0.5%

 

 0.23%

 

5. SPECIFIC OPTICAL ROTATION  

 

-4.5º ~ -5.5º

 

 -5.1º

 

6.HEAVY METALS

 

20PPM

 

 20PPM

 

7.RESIDUAL SOLVENTS  

 

MEETS THE REQUIREMENTS

 

 COMPLIES

 

8.ASSAY(HPLC)

 

98.50%

 

 99.70%

 

CONCLUSION COMPLIES WITH  Enterprise standard

 

QC DEPT.:Wang Shijun           ANALYST:Li Ye         CHECKER: Ying Xiaomei
   
  KEY INTERMEDIATES    
 
  Intermediate of fosinopril 
Trans-4-cyclohexyl-l-proline hydrochloride  CAS:90657-55
Molecular formula : C11H20ClNO2
Molecular weight:

233.735

Structure
 
98.5%
Assay :
   
  Applications    
   Fosinopril is in a class of drugs called ace inhibitors which inhibit ace and block the formation of angiotensin ii. It is used in the treatment of high blood pressure and congestive heart failure. more....
   
  Packing &loading    
       
        This data is only for your information purposes and does not imply guarantee for a certain application.    
       If you need an indicative price to your country, please kindly advise the annual quantity needed, destination port and we will send you our soonest CNF(Cost + Freight) price. Your indication for a workable price level will sure speed up our fastest service for you    
 

     We really need to get feed back from our customers in order to improve our performances.
Any information about quotations from competitors will be welcomed since we hope to work as a team with you.
Your kind help will be very much appreciated.

     Best regards from SHENZHEN , China

                                                       Mr. JEFFERY TSUI

   
       
  Material Safety Data Sheet    
       
  Related Information and materials    
 

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