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MEPIVACAINE HCl

PRODUCT IDENTIFICATION
CAS NO. 22801-44-1 (Base), MEPIVACAINE HCl
1722-62-9 (HCl)
EINECS NO.
FORMULA C15H23ClN2O
MOL WT. 282.8125
H.S. CODE
DERIVATION
TOXICITY
SYNONYMS Carbocaine Hydrochloride; 
N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide monohydrochloride; 
CLASSIFICATION
PHYSICAL AND CHEMICAL PROPERTIES 
PHYSICAL STATE White crystalline powder
MELTING POINT  255 - 265 C
BOILING POINT
SPECIFIC GRAVITY 
SOLUBILITY IN WATER
pH 4-5
VAPOR DENSITY
AUTOIGNITION
NFPA RATINGS
REFRACTIVE INDEX
FLASH POINT
STABILITY Stable under ordinary conditions.
GENERAL DESCRIPTION & APPLICATIONS
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide  is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest). 
SALES SPECIFICATION 
Ph Eur/USP
APPEARANCE White crystalline powder
ASSAY 98.5 - 101.0%
MELTING POINT 255 - 265 C
LOSS ON DRYING 0.3% max
RESIDUE ON IGNITION 0.1% max
HEAVY METALS 20ppm max
TRANSPORTATION
PACKING 25kgs in fiber drum
HAZARD CLASS
UN NO.
OTHER INFORMATION
European Hazard Symbols: , Risk Phrases: 36/37/38, Safety Phrases: 22-26-36
   
   
   
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                                                       Mr. JEFFERY TSUI

   
       
  Material Safety Data Sheet    
       
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