CAS Registry Number:143-67-9

Usage:

Used for preparation of Vinblastine Sulfate for Injection.

Storage:

Preserve in tightly closed containers, stored in a cool place and protected from light.

Packing:

50kg/bottle

Specification:

BP 2002, USP 26, CP 2000

Description:

A white or almost white crystalline powder; odourless; hydroscopic; discoloured on exposure to light or heat.

Action and indications:

Vinblastine sulfate is an alkaloid extracted from Vinca rosea. As a cell cycle specific drug, it can inhibit growth of neoplasm and formation of proliferating cell spindle, as a result, mitosis is stopped at its metaphase . Clinically, it is similar to vincristine sulfate in effects, no cross tolerance is found between the two drugs. It has a better effect in the treatment of malignant lymphoma , especially lymphoreticular cell sarcoma, Hodgkin's disease, chorioepithelioma, breast carcinoma, head and neck cancer, oropharynx cancer, neuroblastoma, monocytic leukemia , lung cancer , cervix cancer, and alimentary tract tumor, and has some effect in lymphoma, nephroblastoma and melanoma.