Phloroglucinol dihydrate

Phloroglucinol dihydrate

1.  DESCRIPTION:

Synonyms: 1,3,5-Trihydroxybenzene dihydrate, 1,3,5-THB dihyrate

CAS No.: 6099-90-7

Molecular Weight: 162.14

Molecular Formula: C6H6O3.2H2O

2.

CERTIFICATE OF ANALYSIS:

TEST                                LOT {SAMPLE} RESULTS

m.p.: 218~221 deg. C

Usage: pharmaceutical, dye intermediate, etc

 Purity Grade: puriss., >= 99.0 % (HPLC)

Comments: mp 217— 219 °C

ASSAY (HPLC)             99.0 % REL 

APPEARANCE              FAINTLY BEIGE POWDER

SOLUBILITY (COLOUR) VERY FAINTLY GREENISH-YELLOW

SOLUBILITY (TURBIDITY)  CLEAR (<3.5 NTU)

Water(%): NMT:0.5%

If for Pharm grade,

CL-           no more than 200ppm

SO4-   no more than 500ppm

The metal(Pb) no more than 20ppm

     We really need to get feed back from our customers in order to improve our performances.
Any information about quotations from competitors will be welcomed since we hope to work as a team with you.
Your kind help will be very much appreciated.

     Best regards from SHENZHEN , China

                                                       Mr. JEFFERY TSUI

       SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -

    CATALOG #:            79330

    NAME:                 PHLOROGLUCINOL, DIHYDRATE FREE OF DIRESORCIN

SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -

    1,3,5-Trihydroxybenzene dihydrate, 1,3,5-THB

CAS No.: 6099-90-7

SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -

  LABEL PRECAUTIONARY STATEMENTS

    IRRITANT

    IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.

    RISK OF SERIOUS DAMAGE TO EYES.

    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF

    WATER AND SEEK MEDICAL ADVICE.

    WEAR SUITABLE PROTECTIVE CLOTHING.

SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -

    IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS

    AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED

    CLOTHING AND SHOES.

    IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.

    CALL A PHYSICIAN.

    IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL

    RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.

    ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS

    WITH FINGERS.

SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -

  EXTINGUISHING MEDIA

    WATER SPRAY.

    CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.

  SPECIAL FIREFIGHTING PROCEDURES

    WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO

    PREVENT CONTACT WITH SKIN AND EYES.

SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -

    WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY

    RUBBER GLOVES.

    SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.

    AVOID RAISING DUST.

    VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -

    REFER TO SECTION 8.

SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -

    WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT

    GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.

    MECHANICAL EXHAUST REQUIRED.

    SAFETY SHOWER AND EYE BATH.

    DO NOT BREATHE DUST.

    AVOID CONTACT WITH EYES, SKIN AND CLOTHING.

    AVOID PROLONGED OR REPEATED EXPOSURE.

    WASH THOROUGHLY AFTER HANDLING.

    KEEP TIGHTLY CLOSED.

    STORE IN A COOL DRY PLACE.

SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -

  PHYSICAL PROPERTIES

    FLASHPOINT               57.20F

                             14C

    SPECIFIC GRAVITY:     0.801

SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -

  INCOMPATIBILITIES

    ACID CHLORIDES

    ACID ANHYDRIDES

    BASES

    OXIDIZING AGENTS

  HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS

    CARBON MONOXIDE, CARBON DIOXIDE

SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -

  ACUTE EFFECTS

    CAUSES SKIN IRRITATION.

    CAUSES SEVERE EYE IRRITATION.

    MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER

    RESPIRATORY TRACT.

    MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.

    TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND

    TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.

  RTECS #: SY1050000

    PHLOROGLUCINOL

  TOXICITY DATA

    ORL-RAT LD50:4 GM/KG                          THERAP 17,1349,1962

    IPR-RAT LD50:3180 MG/KG                       NIIRDN 6,740,1982

    SCU-RAT LD50:4850 MG/KG                       NIIRDN 6,740,1982

    ORL-MUS LD50:4550 MG/KG                       OYYAA2 3,187,1969

    IPR-MUS LD50:4050 MG/KG                       OYYAA2 3,187,1969

    SCU-MUS LD50:991 MG/KG                        ZGIMAL 2,333,1947

  TARGET ORGAN DATA

    MATERNAL EFFECTS (OVARIES, FALLOPIAN TUBES)

    ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES

    (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR

    COMPLETE INFORMATION.

SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -

    DATA NOT YET AVAILABLE.

SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -

    DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A

    CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.

    OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -

    CONTACT FLUKA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.

SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -

  EUROPEAN INFORMATION

    IRRITANT

    R 36/37/38

    IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.

    R 41

    RISK OF SERIOUS DAMAGE TO EYES.

    S 26

    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF

    WATER AND SEEK MEDICAL ADVICE.

    S 36

    WEAR SUITABLE PROTECTIVE CLOTHING.

  REVIEWS, STANDARDS, AND REGULATIONS

    OEL=MAK

    NOHS 1974: HZD M1900; NIS 28; TNF 931; NOS 16; TNE 4964

    NOES 1983: HZD M1900; NIS 5; TNF 82; NOS 4; TNE 2785; TFE 1381

    EPA TSCA SECTION 8(B) CHEMICAL INVENTORY

    EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES

    EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -

    THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO

    BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,

    FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING

    OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR

    PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.

    COPYRIGHT 2001 SIGMA-ALDRICH CO.

    LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY